Primary immunodeficiencies (PIDs), also known as inborn errors of immunity (IEI) include more than 400 potentially serious disorders that can lead to frequent or severe infections, swellings (hereditary angioedema [HAE]) and autoimmune problems. PID/IEI discorders can be caused by defects in genes that control the immune system, and may be inherited. 

Note: ASCIA Immunoglobulin Replacement Therapy (IRT) and Subcutaneous Immunoglobulin (SCIg) information is mostly not specific for PID, and can be used by other medical specialties. 

Information for Health Professionals

ASCIA Immunodeficiency e-training courses - PID, IRT*, HAE* *New 2022

Primary Immunodeficiencies (PIDs)

ASCIA Immunodeficiency Strategy for Australia and New Zealand Launched May 2022

ASCIA Guidelines for Diagnosis and Management of Severe Combined Immunodeficiency (SCID) in Australia and New Zealand: A TAPID Consensus Guideline

ASCIA PID Clinical Update 

References - Immunodeficiency

ASCIA ID Register How to access information (available to ASCIA members only)

Immunoglobulin Replacement Therapy (IRT) 

ASCIA Position Statement - IRT in PID Updated August 2022

ASCIA Guidelines - Standardised IVIg Infusion Rates for IRT Updated April 2023 

ASCIA Transfer Care Plan for patients on IRT

Subcutaneous Immunoglobulin (SCIg)

ASCIA SCIg Checklists - Nurse Competency and Patient Training 

ASCIA SCIg Treatment Plan

ASCIA Travel Plan for patients on SCIg

ASCIA SCIg Position Statement  

ASCIA Guide – Setting up a SCIg program in a hospital

Hereditary Angioedema (HAE)

ASCIA HAE Position Paper and Management Plan Updated October 2022

References - HAE

ASCIA Webinar - HAE

Further Information

Webpage updated April 2023

Mod ASCIA Member
Donate to AIFA
go to NAC website

ASCIA is the peak professional body of clinical immunology and allergy in Australia and New Zealand
ASCIA promotes and advances the study and knowledge of allergy and other immune diseases

Quick Links


ASCIA is a registered trademark of the Australasian Society of Clinical Immunology and Allergy. All content is subject to copyright for the Australasian Society of Clinical Immunology and Allergy. Read more...

The content for the website is developed and approved by ASCIA Committee and ASCIA Working Party Members. Read more...

Disclaimer I Privacy

The ASCIA website is intended for use by ASCIA members, health professionals and the general public. The content provided is for education, communication and information purposes only and is not intended to replace or constitute medical advice or treatments. Read more...

ASCIA respects your privacy. Read our privacy policy here...

Sponsors | Advertising

ASCIA does not endorse products from sponsoring organisations, nor is it influenced by sponsoring organisations with regard to the content of education programs and websites. 

The ASCIA website does not accept advertising. Any link to a third-party website does not imply any endorsement by ASCIA.

Information Partner

Official Information Partner of Healthdirect Australia