Autoimmune Diseases

pdfASCIA Fast Facts Autoimmune Diseases 2019377.38 KB

  1. Autoimmune DiseasesAutoimmune diseases are a broad range of more than 80 related disorders that range from common to rare. They affect around 5% of people and are one of the most important chronic health problems in Australia and New Zealand. Common autoimmune diseases such as thyroiditis, rheumatoid arthritis and diabetes affect more than 1% of people. Lupus (SLE) affects less than 0.1% of people and is more common and severe in Indigenous Australians, Polynesians and people descended from South East Asia.
  1. In autoimmune diseases the immune system produces an inappropriate response against its own cells, tissues and/or organs, resulting in inflammation and damage. This can be localised to a single organ in the body or generalised (systemic), affecting many organs and tissues in the body. Whilst the tendency for autoimmunity may be inherited in some people, factors such as infections and some drugs can play a role in triggering autoimmune diseases.
  1. Localised (organ specific) autoimmune diseases mainly affect a single organ and/or tissue. However, the effects frequently extend to other body systems and organs. These diseases are often managed by organ-specific medical specialists, such as endocrinologists, gastroenterologists, neurologists or rheumatologists.
  1. Systemic autoimmune diseases can affect many body organs and tissues at the same time. They can be broadly classified into rheumatological disease and vasculitis disorders (inflammation of blood vessels). These diseases are often managed by clinical immunology/allergy specialists and/or rheumatologists.
  1. Autoimmune diseases are usually diagnosed using a combination of clinical history, blood tests (autoantibodies, inflammation, organ function) and other investigations such as x-rays. Sometimes a biopsy of affected tissues may be required for diagnosis.
  1. There is a wide range of treatment options, which depend on the stage and type of autoimmune disease. The main aims of treatments are to relieve symptoms, minimise organ and tissue damage and preserve organ function. Treatment options include:
    - Replacement of end organ functions (such as insulin in diabetes)
    - Non-steroidal anti-inflammatory medications (NSAIDS)
    - Corticosteroid anti-inflammatory medications (such as Prednisolone)
    - Immunosuppressive medications
    - Therapeutic monoclonals (such as TNF inhibitors)
    - Immunoglobulin replacement therapy (IRT)

For more information visit www.allergy.org.au/patients/autoimmunity

There are several patient support organisations for autoimmune disorders that offer information and support. Some of these are listed on the ASCIA website www.allergy.org.au/patients/patient-support-organisations

© ASCIA 2019

ASCIA is the peak professional body of clinical immunology/allergy specialists in Australia and New Zealand

Website: www.allergy.org.au 
Email: This email address is being protected from spambots. You need JavaScript enabled to view it. 
Postal address: PO Box 450 Balgowlah NSW 2093 Australia

Disclaimer
This document has been developed and peer reviewed by ASCIA members and is based on expert opinion and the available published literature at the time of review. Information contained in this document is not intended to replace medical advice and any questions regarding a medical diagnosis or treatment should be directed to a medical practitioner. Development of this document is not funded by any commercial sources and is not influenced by commercial organisations.

Content updated February 2019

Mod ASCIA Member
Donate to AIFA
go to NAC website
About ASCIA

ASCIA is the peak professional body of clinical immunology and allergy in Australia and New Zealand
ASCIA promotes and advances the study and knowledge of allergy and other immune diseases

Quick Links

About ASCIA

ASCIA is a registered trademark of the Australasian Society of Clinical Immunology and Allergy. All content is subject to copyright for the Australasian Society of Clinical Immunology and Allergy. Read more...

The content for the website is developed and approved by ASCIA Committee and ASCIA Working Party Members. Read more...

Disclaimer I Privacy

The ASCIA website is intended for use by ASCIA members, health professionals and the general public. The content provided is for education, communication and information purposes only and is not intended to replace or constitute medical advice or treatments. Read more...

ASCIA respects your privacy. Read our privacy policy here...

Sponsors | Advertising

ASCIA does not endorse products from sponsoring organisations, nor is it influenced by sponsoring organisations with regard to the content of education programs and websites. 

The ASCIA website does not accept advertising. Any link to a third-party website does not imply any endorsement by ASCIA.

Information Partner

Official Information Partner of Healthdirect Australia